New Wheels for Grandma

What's Best for Grandma?

Miro1: new wheels for transferring mitochondria.

Mesenchymal stem cells (MSC) are capable of protecting cells harboring mitochondrial damage. This protection is associated with the transfer of mitochondria through tunneling nanotubes (TNT) from MSC to the injured cells. In this issue of The EMBO Journal, the group of Anurag Agrawal shows that mitochondrial transfer is dependent on the levels of Miro1, a mitochondrial Rho-GTPase that regulates...

Cyclins: wheels within wheels.

Cycimns were originally defined as proteins which are synthesized in each cell cycle and destroyed at every mitosis. Cyclins were discovered by T. Hunt and students at the Marine Biological Laboratory, Woods Hole, MA, duningthe 1982 Physiology Course (1). They labeled eggs ofthe sea urchin Arbacia punctulata with [35S]methionine after fertilization and analyzed the temporal pattern of protein s...

a new approach to credibility premium for zero-inflated poisson models for panel data

هدف اصلی از این تحقیق به دست آوردن و مقایسه حق بیمه باورمندی در مدل های شمارشی گزارش نشده برای داده های طولی می باشد. در این تحقیق حق بیمه های پبش گویی بر اساس توابع ضرر مربع خطا و نمایی محاسبه شده و با هم مقایسه می شود. تمایل به گرفتن پاداش و جایزه یکی از دلایل مهم برای گزارش ندادن تصادفات می باشد و افراد برای استفاده از تخفیف اغلب از گزارش تصادفات با هزینه پائین خودداری می کنند، در این تحقیق ...

Wheels within wheels: new transcriptional feedback loops in the Arabidopsis circadian clock

The circadian clock allows organisms to temporally coordinate their biology with the diurnal oscillation of the environment, which enhances plant performance. Accordingly, a fuller understanding of the circadian clock mechanism may contribute to efforts to optimize plant performance. One recurring theme in clock mechanism is coupled transcription-translation feedback loops. To date, the majorit...